Barrett’s esophagus risk for malignancy

esophagus risk for malignancyThe esophagus is the muscular tube connecting the pharynx to the stomach. Long is 25-30 cm and e internally coated with mucosa. The function of the esophagus is to move solids and liquids towards the stomach. The lower esophageal sphincter (LES) is a circular muscle that lies on the border between the esophagus and stomach. It provides protection from the possible return of already located in the stomach food. These and various other anatomical features of the digestive system and provide movement of ingested food in only one direction – from the mouth to the colon. We have repeatedly drawn attention to the disease gastroesophageal reflux disease. In the main it is that precisely this defense – the lower esophageal sphincter does not work and this leads to regurgitation of gastric contents into the esophagus. Besides the unpleasant sensation of heartburn (burning pain behind the chest wall), this pathological process may be much more dangerous effect on human health. Any unnatural movement of food in the body leaves its consequences. In the case could lead to t. Pomegranate. Barrett’s esophagus.

What happens when the delicate lining of the esophagus is less than the continuous influence of hydrochloric acid from the stomach?
Prepared progressive inflammation of the mucous membrane, leading to its change (metaplasia) and converts it into intestinal – i.e. characteristic of intestinal department. Patients with Barrett’s esophagus risk for developing adenocarcinoma of the esophagus is much larger. Let’s note that not everyone diagnosed with GERD develop Barrett’s esophagus, and vice versa – not everyone with Barrett’s esophagus have gestroezofagealna reflux disease. Chronic GERD is a serious precondition for the emergence of the aforementioned complications. Other reasons may be mentioned as a condition for appearance of Barrett’s esophagus are: asthmatic diseases, pregnancy, mental disorders (bulimia), various stressful situations, metabolic diseases, smoking and others. The symptoms are heartburn and all subjective sensations that arise, shortness of breath, cough. As shown clinical manifestations are not specific to a diagnosis only by them. At exactly Barrett’s esophagus is diagnosed by endoscopy and taking material for biopsy.

American Association of Gastroenterologists advised to make screening people at increased risk for this disease: age over 50, male sex, presence of hiatal hernia, gastroesophageal reflux disease for a long time, overweight with fat accumulation in the abdomen. Important in screening is to understand than whether it is for Barrett’s esophagus, but also whether there are existing cancer cells.

When you put such a diagnosis with no evidence of malignancy of the process, the goal of treatment is to stop the irritation of esophageal mucosa and its modification. This is being taken against the return of stomach acid into the esophagus. We need the patient to make some changes in your diet, avoiding fatty foods, caffeine, chocolate and spicy things. It should also avoid alcohol and smoking, to maintain normal weight, to sleep higher and not eat 2-3 hours before bedtime, and to take prescribed medication for heartburn. This lifestyle is recommended to be observed before the onset of the disease by prevention.

There is also a specific treatment for Barrett’s esophagus. It can be accomplished in the following ways:
Radiofrequency ablation – using radio waves destroyed the modified cells and normal are preserved.
Photodynamic therapy – laser to kill the abnormal cells and healthy again retained.
Endoscopic cryotherapy.
Removing part of the esophagus – this is usually undertaken when there is a presence of precancerous or cancerous cells.